Trichloroethylene, a chemical once widely used in household and industrial products, has been linked to a significant increase in the risk of developing Parkinson’s disease, according to an April 18 statement by SciTechDaily.
Parkinson’s disease is a chronic condition that causes tremors, muscle rigidity, and problems with balance and coordination. These symptoms can make everyday tasks difficult for those affected.
The chemical trichloroethylene (TCE) is classified as a human carcinogen. It was commonly used in dry cleaning, paint removers, household cleaners, and even decaffeinated coffee. Its use dates back over a century after it was first synthesized in the 19th century as an industrial solvent.
Exposure to TCE has been associated with several serious health conditions including miscarriages, congenital heart defects, kidney cancer, liver cancer, non-Hodgkin lymphoma—and now a notably higher risk of developing Parkinson’s disease later in life. Researchers from the University of Rochester Medical Center have published findings suggesting that TCE may be underestimated as a cause of Parkinson’s because many patients were exposed decades before symptoms appeared.
People without occupational exposure can also encounter TCE through environmental contamination. For example, lawsuits related to Camp Lejeune alleged that contaminated water supplies contributed to cases of Parkinson’s disease and other illnesses among residents.
To address these risks, the Biden administration banned the manufacture, importation and processing of TCE after an Environmental Protection Agency report found continued dangers. The rule took effect in March 2025 following delays caused by President Donald Trump’s “Regulatory Freeze Pending Review” memorandum. The EPA continues to release updates on regulations for toxic chemicals like TCE.
